Why would a woman take progesterone? It's a crucial part of the menstrual cycle and maintenance of pregnancy. Progesterone helps to regulate your cycle. But its main job is to get your uterus ready for pregnancy. After you ovulate each month, progesterone helps thicken the lining of the uterus to prepare for a fertilized egg. What are the side effects from estradiol? Side Effects. Stomach upset, nausea/vomiting, bloating, breast tenderness, headache, or weight changes may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. What are hot flashes a sign of? Hot flashes are sudden feelings of warmth, which are usually most intense over the face, neck and chest. Your skin might redden, as if you're blushing. Hot flashes can also cause sweating, and if you lose too much body heat, you might feel chilled afterward.
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